What is the best option for long-term memory retention?

The recommended option to review is Bacopa.

What is the best option for neurogenesis / brain growth?

The recommended option to review is Lions Mane.

What is the best option for acetylcholine support / speed?

The recommended option to review is Alpha-GPC.

Goal decision guide

Cognitive enhancement decisions

Evaluate options targeting long-term memory consolidation, neuroprotection, and information processing speed.

How to read this guide

These comparisons are educational triage notes, not treatment instructions. They are meant to help you compare evidence strength, tolerance issues, and practical tradeoffs before reading the full profile or speaking with a qualified clinician.

Research methodology →Evidence hierarchy →Disclaimer →

Quick Comparison Notes

These are starting points for comparison, not recommendations, prescriptions, or guaranteed outcomes.

Use-case context	Option to review
Long-term memory retention	Bacopa
Neurogenesis / brain growth	Lions Mane
Acetylcholine support / speed	Alpha-GPC

Comparison Table

Compound	Potential fit	Typical timing window	Evidence context	Caution level
Lavender Extract	Goal support	Timing varies	Preliminary evidence	Use caution
Bacopa	Long-term memory acquisition and retention	4 to 12 weeks	Strong evidence	Needs review
Devils Claw Extract	Goal support	Timing varies	Preliminary evidence	Use caution
Glycinate Magnesium Complex	Goal support	Timing varies	Preliminary evidence	Use caution
Iberogast	Goal support	Timing varies	Preliminary evidence	Use caution
Maca (Lepidium meyenii)	Goal support	Timing varies	Moderate evidence	Use caution
Passionflower Extract	Goal support	Timing varies	Preliminary evidence	Use caution
Blueberry	Goal support	Timing varies	Strong evidence	Use caution
Hawthorn Extract	Goal support	Timing varies	Preliminary evidence	Use caution
Lion's Mane	Goal support	Timing varies	Moderate evidence	Use caution
Huperzia Serrata	Goal support	Timing varies	Strong evidence	Use caution
L Norvaline	Goal support	Timing varies	Preliminary evidence	Use caution
Lion’s Mane	BDNF support, neuroplasticity, and brain health	2 to 8 weeks	Preliminary evidence	Needs review
Nicotiana Glauca	Goal support	Timing varies	Limited evidence	Use caution
Valerian	Goal support	Timing varies	Moderate evidence	Use caution
5-HTP	Goal support	Timing varies	Moderate evidence	Use caution
acetate	Goal support	Timing varies	Strong evidence	Use caution
Acetyl-L-Carnitine	Goal support	Timing varies	Preliminary evidence	Use caution
Agaricus blazei	Goal support	Timing varies	Limited evidence	Use caution
Agmatine sulfate	Goal support	Timing varies	Preliminary evidence	Use caution
Alkylamides	Goal support	Timing varies	Moderate evidence	Use caution
Allicin	Goal support	Timing varies	Moderate evidence	Use caution
alpha-asarone	Goal support	Timing varies	Limited evidence	Use caution
Alpha-GPC	Rapid choline donation and focus stacking	30 to 90 minutes	Preliminary evidence	Needs review
Amanita muscaria	Goal support	Timing varies	Preliminary evidence	Use caution
American Ginseng Extract	Goal support	Timing varies	Preliminary evidence	Use caution
American Yellow Lotus	Goal support	Timing varies	Limited evidence	Use caution
anabasine	Goal support	Timing varies	Limited evidence	Use caution
anatabine	Goal support	Timing varies	Limited evidence	Use caution
Angelica Dahurica	Goal support	Timing varies	Limited evidence	Use caution
arjunolic acid	Goal support	Timing varies	Limited evidence	Use caution
Ashitaba Extract	Goal support	Timing varies	Strong evidence	Use caution
aspalathin	Goal support	Timing varies	Strong evidence	Use caution
astragaloside iv	Goal support	Timing varies	Strong evidence	Use caution
atractylenolide i	Goal support	Timing varies	Limited evidence	Use caution
atractylenolide iii	Goal support	Timing varies	Limited evidence	Use caution
Bacopa extract standardized	Goal support	Timing varies	Moderate evidence	Use caution
bacopaside ii	Goal support	Timing varies	Moderate evidence	Use caution
bacoside a	Goal support	Timing varies	Limited evidence	Use caution
bacoside b	Goal support	Timing varies	Limited evidence	Use caution
Beta-sitosterol	Goal support	Timing varies	Preliminary evidence	Use caution
Betaine	Goal support	Timing varies	Preliminary evidence	Use caution
beta- hydroxybutyrate	Goal support	Timing varies	Moderate evidence	Use caution
Bilberry Extract	Goal support	Timing varies	Preliminary evidence	Use caution
bilobetin	Goal support	Timing varies	Limited evidence	Use caution
Burdock Root	Goal support	Timing varies	Limited evidence	Use caution
Caffeine	Goal support	Timing varies	Moderate evidence	Use caution
caffeine l-theanine	Goal support	Timing varies	Strong evidence	Use caution
Capsicum Frutescens	Goal support	Timing varies	Needs review	Use caution
Cayenne	Goal support	Timing varies	Limited evidence	Use caution
Citicoline / CDP-choline	Goal support	Timing varies	Preliminary evidence	Use caution
Celastrus Paniculatus	Goal support	Timing varies	Limited evidence	Use caution
charantin	Goal support	Timing varies	Strong evidence	Use caution
Choline	Goal support	Timing varies	Preliminary evidence	Use caution
Citicoline	Goal support	Timing varies	Needs review	Use caution
Cnidium Monnieri	Goal support	Timing varies	Limited evidence	Use caution
vitamin b12	Goal support	Timing varies	Preliminary evidence	Use caution
Coconut Oil	Goal support	Timing varies	Strong evidence	Use caution
Ubiquinol CoQ10	Goal support	Timing varies	Preliminary evidence	Use caution
Curcumin phytosome	Goal support	Timing varies	Preliminary evidence	Use caution
Curcumin + piperine	Goal support	Timing varies	Preliminary evidence	Use caution
desmethoxyyangonin	Goal support	Timing varies	Limited evidence	Use caution
DHEA	Goal support	Timing varies	Preliminary evidence	Use caution
Dietary Nitrates	Goal support	Timing varies	Moderate evidence	Use caution
dihydrokavain	Goal support	Timing varies	Limited evidence	Use caution
dihydromethysticin	Goal support	Timing varies	Limited evidence	Use caution
EGCG + Caffeine	Goal support	Timing varies	Moderate evidence	Use caution
Estrogen Balance Stack	Goal support	Timing varies	Preliminary evidence	Use caution
GABA (Oral)	Goal support	Timing varies	Moderate evidence	Use caution
Galantamine	Goal support	Timing varies	Preliminary evidence	Use caution
Ginkgo	Goal support	Timing varies	Strong evidence	Use caution
ginkgolide b	Goal support	Timing varies	Moderate evidence	Use caution
Ginkgolides	Goal support	Timing varies	Moderate evidence	Use caution
Glycine	Goal support	Timing varies	Moderate evidence	Use caution
Glycine (Sleep Use)	Goal support	Timing varies	Moderate evidence	Use caution
Graviola (Annona muricata)	Goal support	Timing varies	Limited evidence	Use caution
Guayusa	Goal support	Timing varies	Limited evidence	Use caution
gurmarin	Goal support	Timing varies	Limited evidence	Use caution
gymnemic acid	Goal support	Timing varies	Limited evidence	Use caution
Harmaline	Goal support	Timing varies	Limited evidence	Use caution
Harmine	Goal support	Timing varies	Limited evidence	Use caution
HCG Diet	Goal support	Timing varies	Strong evidence	Use caution
hericenones	Goal support	Timing varies	Limited evidence	Use caution
Huperzine A	Goal support	Timing varies	Preliminary evidence	Use caution
huperzine b	Goal support	Timing varies	Limited evidence	Use caution
Hyperforin	Goal support	Timing varies	Strong evidence	Use caution
Ibogaine	Goal support	Timing varies	Limited evidence	Use caution
imperatorin	Goal support	Timing varies	Limited evidence	Use caution
Iodine	Goal support	Timing varies	Preliminary evidence	Use caution
isoimperatorin	Goal support	Timing varies	Limited evidence	Use caution
Ketamine	Goal support	Timing varies	Limited evidence	Use caution
Kratom	Goal support	Timing varies	Limited evidence	Use caution
arginine	Goal support	Timing varies	Preliminary evidence	Use caution
L-theanine	Goal support	Timing varies	Moderate evidence	Use caution
L-Theanine (Sleep Use)	Goal support	Timing varies	Moderate evidence	Use caution
L-Tyrosine	Goal support	Timing varies	Preliminary evidence	Use caution
lagerstroemin	Goal support	Timing varies	Strong evidence	Use caution
Lavender	Goal support	Timing varies	Moderate evidence	Use caution
Lecithin	Goal support	Timing varies	Preliminary evidence	Use caution
Lemon Balm Extract	Goal support	Timing varies	Preliminary evidence	Use caution
linalool	Goal support	Timing varies	Limited evidence	Use caution
Lithium Orotate	Goal support	Timing varies	Limited evidence	Use caution
Lobelia Inflata	Goal support	Timing varies	Limited evidence	Use caution
lobeline	Goal support	Timing varies	Limited evidence	Use caution
Lycopene	Goal support	Timing varies	Preliminary evidence	Use caution
Maca Root Extract	Goal support	Timing varies	Preliminary evidence	Use caution
magnolol	Goal support	Timing varies	Limited evidence	Use caution
Manganese	Goal support	Timing varies	Moderate evidence	Use caution
Matcha	Goal support	Timing varies	Preliminary evidence	Use caution
methyl eugenol	Goal support	Timing varies	Limited evidence	Use caution
methyleugenol	Goal support	Timing varies	Limited evidence	Use caution
methysticin	Goal support	Timing varies	Limited evidence	Use caution
momordicoside k	Goal support	Timing varies	Strong evidence	Use caution
mulberroside a	Goal support	Timing varies	Limited evidence	Use caution
Myristica Fragrans	Goal support	Timing varies	Limited evidence	Use caution
myristicin	Goal support	Timing varies	Limited evidence	Use caution
NAC	Goal support	Timing varies	Preliminary evidence	Use caution
Nicotiana Tabacum	Goal support	Timing varies	Limited evidence	Use caution
nicotine	Goal support	Timing varies	Limited evidence	Use caution
Noopept	Goal support	Timing varies	Preliminary evidence	Use caution
Nutmeg (Myristica fragrans)	Goal support	Timing varies	Limited evidence	Use caution
Omega-3 fatty acids	Goal support	Timing varies	Strong evidence	Use caution
Omega-3 DHA-Dominant	Goal support	Timing varies	Moderate evidence	Use caution
Omega-3 EPA	Goal support	Timing varies	Strong evidence	Use caution
Omega-3 EPA-Dominant	Goal support	Timing varies	Moderate evidence	Use caution
Panax Ginseng Extract	Goal support	Timing varies	Preliminary evidence	Use caution
American Ginseng	Goal support	Timing varies	Moderate evidence	Use caution
Pantethine	Goal support	Timing varies	Moderate evidence	Use caution
Passionflower	Goal support	Timing varies	Preliminary evidence	Use caution
Passionflower Extract (Standardized)	Goal support	Timing varies	Limited evidence	Use caution
Phenylalanine	Goal support	Timing varies	Preliminary evidence	Use caution
Phloretin	Goal support	Timing varies	Preliminary evidence	Use caution
Phosphatidylcholine	Goal support	Timing varies	Preliminary evidence	Use caution
Black Pepper	Goal support	Timing varies	Strong evidence	Use caution
Pomegranate Extract	Goal support	Timing varies	Preliminary evidence	Use caution
Pregnenolone	Goal support	Timing varies	Limited evidence	Use caution
Bifidobacterium Probiotic	Goal support	Timing varies	Preliminary evidence	Use caution
propionate	Goal support	Timing varies	Moderate evidence	Use caution
Psilocybin	Goal support	Timing varies	Limited evidence	Use caution
puerarin	Goal support	Timing varies	Strong evidence	Use caution
putrescine	Goal support	Timing varies	Moderate evidence	Use caution
Pyridoxal-5-phosphate	Goal support	Timing varies	Strong evidence	Use caution
Rhodiola	Goal support	Timing varies	Moderate evidence	Use caution
Rosemary	Goal support	Timing varies	Limited evidence	Use caution
safranal	Goal support	Timing varies	Limited evidence	Use caution
SAM-e	Goal support	Timing varies	Preliminary evidence	Use caution
serine	Goal support	Timing varies	Moderate evidence	Use caution
Shilajit Extract	Goal support	Timing varies	Preliminary evidence	Use caution
Tanshinone IIA	Goal support	Timing varies	Limited evidence	Use caution
Taurine	Goal support	Timing varies	Strong evidence	Use caution
Testosterone Support Stack	Goal support	Timing varies	Preliminary evidence	Use caution
Tetrahydroharmine	Goal support	Timing varies	Limited evidence	Use caution
THCV	Goal support	Timing varies	Limited evidence	Use caution
theanine	Goal support	Timing varies	Moderate evidence	Use caution
Cacao	Goal support	Timing varies	Strong evidence	Use caution
thujone	Goal support	Timing varies	Limited evidence	Use caution
timosaponin aiii	Goal support	Timing varies	Limited evidence	Use caution
trigonelline	Goal support	Timing varies	Strong evidence	Use caution
Uridine Monophosphate	Goal support	Timing varies	Preliminary evidence	Use caution
Uva Ursi	Goal support	Timing varies	Limited evidence	Use caution
Valerenic Acid	Goal support	Timing varies	Moderate evidence	Use caution
valerenol	Goal support	Timing varies	Limited evidence	Use caution
Valerian Extract (Standardized)	Goal support	Timing varies	Limited evidence	Use caution
Vinpocetine	Goal support	Timing varies	Preliminary evidence	Use caution
Vitamin B3	Goal support	Timing varies	Moderate evidence	Use caution
Vitamin B6	Goal support	Timing varies	Strong evidence	Use caution
yangonin	Goal support	Timing varies	Limited evidence	Use caution
Zeaxanthin	Goal support	Timing varies	Preliminary evidence	Use caution
Gastrodia	Goal support	Timing varies	Limited evidence	Use caution
Jatamansi	Goal support	Timing varies	Limited evidence	Use caution
Polygala	Goal support	Timing varies	Limited evidence	Use caution
Shankhpushpi	Goal support	Timing varies	Limited evidence	Use caution

Runtime Profile Signals

These badges are pulled from existing compound runtime profiles when available. Empty or pending fields stay conservative rather than inventing missing evidence, mechanism, or safety details.

Lavender Extract

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stressNeuroendocrine modulationstress/neuroendocrine

Bacopa

Evidence: Strong evidenceSafety: Needs review

Mechanism tags

AntioxidantNeuroprotective activityOxidative Stress ModulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectredox/mitochondrialnervous system

Devils Claw Extract

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryInflammatory Signaling Modulation

Mechanism categories

corePhysiological effectimmune/inflammatory

Glycinate Magnesium Complex

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stressNeuroendocrine modulationstress/neuroendocrine

Iberogast

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

general phytochemical signaling

Maca (Lepidium meyenii)

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Hormonal signaling contextHPA-axis modulationHormonal Signaling ContextStress Response Modulation

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

Passionflower Extract

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stressNeuroendocrine modulationstress/neuroendocrine

Blueberry

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantMetabolic regulationVascular function support

Mechanism categories

coremetabolicPhysiological effectSignaling pathway modulation

Hawthorn Extract

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Vascular function supportVascular Function Support

Mechanism categories

corePhysiological effectcardiovascular

Lion's Mane

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

Huperzia Serrata

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeurotransmitter ModulationNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

L Norvaline

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Proposed arginase inhibition could theoretically increase arginine availabilitymechanism-only and not human-confirmed.

Lion’s Mane

Evidence: Preliminary evidenceSafety: Needs review

Mechanism tags

Neuroprotective activityNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

Nicotiana Glauca

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neurotransmitter Modulation

Valerian

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stressNeuroendocrine modulationstress/neuroendocrine

5-HTP

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeurotransmitter ModulationNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

acetate

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Metabolic regulationGlucose regulationLipid metabolism supportMetabolic Regulation

Mechanism categories

coremetabolicPhysiological effectMetabolic modulation

Acetyl-L-Carnitine

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryMitochondrial biogenesisMetabolic regulationHormonal signaling context

Mechanism categories

coremitochondrialPhysiological effectPhysiological/cellular effect

Agaricus blazei

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Immune modulationImmune Signaling Modulation

Mechanism categories

immunePhysiological effectimmune-system

Agmatine sulfate

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryVascular function supportNitric oxide modulationInflammatory Signaling Modulation

Mechanism categories

corecardiovascularPhysiological effectSignaling molecule modulation

Alkylamides

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Metabolic regulationImmune modulationLipid metabolism supportMetabolic Regulation

Mechanism categories

coreimmunePhysiological effectmetabolic

Allicin

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

AntioxidantVascular function supportOxidative Stress ModulationVascular Function Support

Mechanism categories

corePhysiological effectredox/mitochondrialcardiovascular

alpha-asarone

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

Alpha-GPC

Evidence: Preliminary evidenceSafety: Needs review

Mechanism tags

Metabolic regulationCellular protectionVascular function supportNeuroprotective activity

Mechanism categories

corePhysiological effectmetaboliccellular resilience

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Amanita muscaria

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

American Ginseng Extract

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Metabolic regulationGlucose regulationMetabolic RegulationGlucose Metabolism Support

Mechanism categories

coremetabolicPhysiological effectMetabolic modulation

American Yellow Lotus

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

AntioxidantHPA-axis modulationOxidative Stress ModulationNeurotransmitter Modulation

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

anabasine

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryInflammatory Signaling ModulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectimmune/inflammatory

anatabine

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryNF-kB inhibitionInflammatory Signaling ModulationNeurotransmitter Modulation

Mechanism categories

coreinflammatoryPhysiological effectSignaling pathway modulation

Angelica Dahurica

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryInflammatory Signaling ModulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectimmune/inflammatory

arjunolic acid

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryMetabolic regulationVascular function supportImmune modulation

Mechanism categories

coreimmunemetabolicinflammatory

Ashitaba Extract

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Metabolic regulationVascular function supportMetabolic RegulationVascular Function Support

Mechanism categories

corePhysiological effectmetaboliccardiovascular

aspalathin

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

AntioxidantMitochondrial biogenesisMetabolic regulationAMPK activation

Mechanism categories

coremitochondrialmetabolicredox

astragaloside iv

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantMitochondrial biogenesisMetabolic regulation

Mechanism categories

coremitochondrialimmunemetabolic

atractylenolide i

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryImmune modulationNF-kB inhibitionInflammatory Signaling Modulation

Mechanism categories

coreimmuneinflammatoryPhysiological effect

atractylenolide iii

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryCellular protectionImmune modulationNF-kB inhibition

Mechanism categories

coreimmuneinflammatoryPhysiological effect

Bacopa extract standardized

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

AntioxidantHormonal signaling contextNeuroprotective activityOxidative Stress Modulation

Mechanism categories

corePhysiological effectredox/mitochondrialendocrine

bacopaside ii

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryMetabolic regulationCellular protectionImmune modulation

Mechanism categories

coreimmunePhysiological effectimmune/inflammatory

bacoside a

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantNeuroprotective activityInflammatory Signaling Modulation

Mechanism categories

corePhysiological effectimmune/inflammatoryredox/mitochondrial

bacoside b

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryMetabolic regulationCellular protectionImmune modulation

Mechanism categories

coreimmunePhysiological effectimmune/inflammatory

Beta-sitosterol

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantMetabolic regulationVascular function support

Mechanism categories

corePhysiological effectimmune/inflammatoryredox/mitochondrial

Betaine

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

general phytochemical signaling

beta- hydroxybutyrate

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Metabolic regulationHPA-axis modulationAMPK activationMetabolic Regulation

Mechanism categories

corestressmetabolicPhysiological effect

Bilberry Extract

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

AntioxidantHPA-axis modulationOxidative Stress ModulationStress Response Modulation

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

bilobetin

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantVascular function supportNF-kB inhibition

Mechanism categories

coreinflammatoryPhysiological effectSignaling pathway modulation

Burdock Root

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantHPA-axis modulationNeuroprotective activity

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

Caffeine

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Vascular function supportHormonal signaling contextHPA-axis modulationNeuroprotective activity

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

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caffeine l-theanine

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Vascular function supportHPA-axis modulationNeuroprotective activityNeurotransmitter Modulation

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

Capsicum Frutescens

Evidence: Needs reviewSafety: Use caution

Cayenne

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryVascular function supportInflammatory Signaling ModulationVascular Function Support

Mechanism categories

corePhysiological effectimmune/inflammatorycardiovascular

Citicoline / CDP-choline

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Metabolic regulationNeuroprotective activityLipid metabolism supportMetabolic Regulation

Mechanism categories

corePhysiological effectmetabolicnervous system

Celastrus Paniculatus

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantHPA-axis modulationNeuroprotective activity

Mechanism categories

corestressinflammatoryPhysiological effect

charantin

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Metabolic regulationAMPK activationGlucose regulationMetabolic Regulation

Mechanism categories

coremetabolicPhysiological effectSignaling pathway modulation

Choline

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Metabolic regulationNeuroprotective activityLipid metabolism supportMetabolic Regulation

Mechanism categories

corePhysiological effectmetabolicnervous system

Citicoline

Evidence: Needs reviewSafety: Use caution

Cnidium Monnieri

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neurotransmitter Modulation

vitamin b12

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Metabolic regulationGlucose regulationMetabolic RegulationGlucose Metabolism Support

Mechanism categories

coremetabolicPhysiological effectMetabolic modulation

Coconut Oil

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Vascular function supportLipid metabolism supportVascular Function SupportLipid Metabolism Support

Mechanism categories

corePhysiological effectcardiovascularmetabolic/cardiovascular

Ubiquinol CoQ10

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

AntioxidantMitochondrial biogenesisVascular function supportHPA-axis modulation

Mechanism categories

coremitochondrialstressPhysiological effect

Curcumin phytosome

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryMetabolic regulationImmune modulationNF-kB inhibition

Mechanism categories

coreimmuneinflammatoryPhysiological effect

Curcumin + piperine

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryInflammatory Signaling Modulation

Mechanism categories

corePhysiological effectimmune/inflammatory

desmethoxyyangonin

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

DHEA

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Hormonal signaling contextHormonal Signaling Context

Mechanism categories

corePhysiological effectendocrine

Dietary Nitrates

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

AntioxidantMitochondrial biogenesisVascular function supportNitric oxide modulation

Mechanism categories

coremitochondrialcardiovascularPhysiological effect

dihydrokavain

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

dihydromethysticin

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

EGCG + Caffeine

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Metabolic regulationVascular function supportAMPK activationGlucose regulation

Mechanism categories

coremetabolicPhysiological effectSignaling pathway modulation

Estrogen Balance Stack

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Hormonal signaling contextHormonal Signaling Context

Mechanism categories

corePhysiological effectendocrine

GABA (Oral)

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

Galantamine

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Neurotransmitter Modulation

Ginkgo

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Vascular function supportNeuroprotective activityVascular Function SupportNeuroprotective Activity

Mechanism categories

corePhysiological effectcardiovascularnervous system

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ginkgolide b

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryVascular function supportNeuroprotective activityInflammatory Signaling Modulation

Mechanism categories

corePhysiological effectimmune/inflammatorycardiovascular

Ginkgolides

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Vascular function supportNeuroprotective activityVascular Function SupportNeuroprotective Activity

Mechanism categories

corePhysiological effectcardiovascularnervous system

Glycine

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

AntioxidantNeuroprotective activityOxidative Stress ModulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectredox/mitochondrialnervous system

Glycine (Sleep Use)

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

inhibitory neurotransmissioncore body temperature reduction

Graviola (Annona muricata)

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Mitochondrial biogenesisNeuroprotective activityMitochondrial SupportNeuroprotective Activity

Mechanism categories

mitochondrialcorePhysiological/cellular effectPhysiological effect

Guayusa

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

AntioxidantOxidative Stress Modulation

Mechanism categories

corePhysiological effectredox/mitochondrial

gurmarin

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Metabolic regulationGlucose regulationMetabolic RegulationGlucose Metabolism Support

Mechanism categories

coremetabolicPhysiological effectMetabolic modulation

gymnemic acid

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Metabolic regulationAMPK activationGlucose regulationMetabolic Regulation

Mechanism categories

coremetabolicPhysiological effectSignaling pathway modulation

Harmaline

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeurotransmitter ModulationNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

Harmine

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

HCG Diet

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Metabolic regulationHormonal signaling contextMetabolic RegulationHormonal Signaling Context

Mechanism categories

corePhysiological effectmetabolicendocrine

hericenones

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

Huperzine A

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryNeuroprotective activityInflammatory Signaling ModulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectimmune/inflammatorynervous system

huperzine b

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryNeuroprotective activityInflammatory Signaling ModulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectimmune/inflammatorynervous system

Hyperforin

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Neurotransmitter Modulation

Ibogaine

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

imperatorin

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantMitochondrial biogenesisInflammatory Signaling Modulation

Mechanism categories

coremitochondrialPhysiological effectPhysiological/cellular effect

Iodine

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Hormonal signaling contextHormonal Signaling Context

Mechanism categories

corePhysiological effectendocrine

isoimperatorin

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantMitochondrial biogenesisInflammatory Signaling Modulation

Mechanism categories

coremitochondrialPhysiological effectPhysiological/cellular effect

Ketamine

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neuroprotective activitymTOR modulationNeuroprotective ActivitymTOR Signaling

Mechanism categories

coremetabolicPhysiological effectSignaling pathway modulation

Kratom

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryInflammatory Signaling Modulation

Mechanism categories

corePhysiological effectimmune/inflammatory

arginine

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Vascular function supportHPA-axis modulationNitric oxide modulationVascular Function Support

Mechanism categories

corestresscardiovascularPhysiological effect

L-theanine

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Vascular function supportHPA-axis modulationNeuroprotective activityNeurotransmitter Modulation

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

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L-Theanine (Sleep Use)

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

L-Tyrosine

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

AntioxidantHormonal signaling contextHPA-axis modulationNeuroprotective activity

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

lagerstroemin

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Metabolic regulationGlucose regulationMetabolic RegulationGlucose Metabolism Support

Mechanism categories

coremetabolicPhysiological effectMetabolic modulation

Lavender

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

Lecithin

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Metabolic regulationCellular protectionHPA-axis modulationLipid metabolism support

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

Lemon Balm Extract

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stressNeuroendocrine modulationstress/neuroendocrine

linalool

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryImmune modulationNeuroprotective activityInflammatory Signaling Modulation

Mechanism categories

coreimmunePhysiological effectimmune/inflammatory

Lithium Orotate

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Hormonal signaling contextNeuroprotective activityHormonal Signaling ContextNeuroprotective Activity

Mechanism categories

corePhysiological effectendocrinenervous system

Lobelia Inflata

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neurotransmitter Modulation

lobeline

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryInflammatory Signaling ModulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectimmune/inflammatory

Lycopene

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

AntioxidantVascular function supportOxidative Stress ModulationVascular Function Support

Mechanism categories

corePhysiological effectredox/mitochondrialcardiovascular

Maca Root Extract

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Hormonal signaling contextHormonal Signaling Context

Mechanism categories

corePhysiological effectendocrine

magnolol

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryImmune modulationNeuroprotective activityNF-kB inhibition

Mechanism categories

coreimmuneinflammatoryPhysiological effect

Manganese

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

AntioxidantMetabolic regulationVascular function supportLipid metabolism support

Mechanism categories

corePhysiological effectredox/mitochondrialmetabolic

Matcha

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Provides caffeine

methyl eugenol

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryCellular protectionInflammatory Signaling ModulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectimmune/inflammatorycellular resilience

methyleugenol

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryCellular protectionNeuroprotective activityInflammatory Signaling Modulation

Mechanism categories

corePhysiological effectimmune/inflammatorycellular resilience

methysticin

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

momordicoside k

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryMetabolic regulationCellular protectionVascular function support

Mechanism categories

coreimmunemetabolicPhysiological effect

mulberroside a

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Metabolic regulationGlucose regulationMetabolic RegulationGlucose Metabolism Support

Mechanism categories

coremetabolicPhysiological effectMetabolic modulation

Myristica Fragrans

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neurotransmitter Modulation

myristicin

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryCellular protectionInflammatory Signaling ModulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectimmune/inflammatorycellular resilience

NAC

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantHPA-axis modulationNeuroprotective activity

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

Nicotiana Tabacum

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

NF-kB inhibitionNeurotransmitter ModulationNF-kB Modulation

Mechanism categories

inflammatorySignaling pathway modulationimmune/inflammatory

nicotine

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryInflammatory Signaling ModulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectimmune/inflammatory

Noopept

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

Nutmeg (Myristica fragrans)

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

Omega-3 fatty acids

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantMetabolic regulationCellular protection

Mechanism categories

corePhysiological effectimmune/inflammatoryredox/mitochondrial

Omega-3 DHA-Dominant

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Metabolic regulationCellular protectionVascular function supportNeuroprotective activity

Mechanism categories

corePhysiological effectmetaboliccellular resilience

Omega-3 EPA

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryMetabolic regulationVascular function supportNeuroprotective activity

Mechanism categories

corePhysiological effectimmune/inflammatorymetabolic

Omega-3 EPA-Dominant

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryMetabolic regulationVascular function supportNeuroprotective activity

Mechanism categories

corePhysiological effectimmune/inflammatorymetabolic

Panax Ginseng Extract

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Metabolic regulationVascular function supportGlucose regulationNitric oxide modulation

Mechanism categories

coremetaboliccardiovascularPhysiological effect

American Ginseng

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Metabolic regulationGlucose regulationMetabolic RegulationGlucose Metabolism Support

Mechanism categories

coremetabolicPhysiological effectMetabolic modulation

Pantethine

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Metabolic regulationVascular function supportLipid metabolism supportMetabolic Regulation

Mechanism categories

corePhysiological effectmetaboliccardiovascular

Passionflower

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

Passionflower Extract (Standardized)

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

Phenylalanine

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Neurotransmitter Modulation

Phloretin

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

AntioxidantMetabolic regulationGlucose regulationOxidative Stress Modulation

Mechanism categories

coremetabolicPhysiological effectMetabolic modulation

Phosphatidylcholine

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Metabolic regulationCellular protectionHPA-axis modulationLipid metabolism support

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

Black Pepper

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Metabolic regulationMetabolic Regulation

Mechanism categories

corePhysiological effectmetabolic

Pomegranate Extract

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

AntioxidantVascular function supportHPA-axis modulationNitric oxide modulation

Mechanism categories

corestresscardiovascularPhysiological effect

Pregnenolone

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Hormonal signaling contextNeurotransmitter ModulationHormonal Signaling Context

Mechanism categories

corePhysiological effectendocrine

Bifidobacterium Probiotic

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryImmune modulationNeuroprotective activityInflammatory Signaling Modulation

Mechanism categories

coreimmunePhysiological effectimmune/inflammatory

propionate

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Metabolic regulationGlucose regulationLipid metabolism supportMetabolic Regulation

Mechanism categories

coremetabolicPhysiological effectMetabolic modulation

Psilocybin

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationStress Response Modulation

Mechanism categories

stressNeuroendocrine modulationstress/neuroendocrine

puerarin

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

AntioxidantMetabolic regulationVascular function supportHormonal signaling context

Mechanism categories

coremetaboliccardiovascularPhysiological effect

putrescine

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Metabolic regulationVascular function supportNitric oxide modulationMetabolic Regulation

Mechanism categories

corecardiovascularPhysiological effectSignaling molecule modulation

Pyridoxal-5-phosphate

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Metabolic regulationNeuroprotective activityMetabolic RegulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectmetabolicnervous system

Rhodiola

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationAMPK activationNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stressmetabolicNeuroendocrine modulationSignaling pathway modulation

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Rosemary

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryAntioxidantNeuroprotective activityAMPK activation

Mechanism categories

coremetabolicinflammatoryredox

safranal

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryCellular protectionNeuroprotective activityInflammatory Signaling Modulation

Mechanism categories

corePhysiological effectimmune/inflammatorycellular resilience

SAM-e

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryVascular function supportInflammatory Signaling ModulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectimmune/inflammatorycardiovascular

serine

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Cellular protectionNeuroprotective activityCellular ProtectionNeuroprotective Activity

Mechanism categories

corePhysiological effectcellular resiliencenervous system

Shilajit Extract

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Mitochondrial biogenesisHormonal signaling contextMitochondrial SupportHormonal Signaling Context

Mechanism categories

mitochondrialcorePhysiological/cellular effectPhysiological effect

Tanshinone IIA

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Vascular function supportNitric oxide modulationVascular Function SupportEndothelial Function Support

Mechanism categories

corecardiovascularPhysiological effectSignaling molecule modulation

Taurine

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

AntioxidantMetabolic regulationVascular function supportHPA-axis modulation

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

Testosterone Support Stack

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Hormonal signaling contextHormonal Signaling Context

Mechanism categories

corePhysiological effectendocrine

Tetrahydroharmine

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeurotransmitter ModulationNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

THCV

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Metabolic regulationGlucose regulationMetabolic RegulationGlucose Metabolism Support

Mechanism categories

coremetabolicPhysiological effectMetabolic modulation

theanine

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

Cacao

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Vascular function supportNitric oxide modulationVascular Function SupportEndothelial Function Support

Mechanism categories

corecardiovascularPhysiological effectSignaling molecule modulation

thujone

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

timosaponin aiii

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Anti-inflammatoryMetabolic regulationCellular protectionVascular function support

Mechanism categories

coreimmunemetabolicPhysiological effect

trigonelline

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

AntioxidantMitochondrial biogenesisMetabolic regulationVascular function support

Mechanism categories

coremitochondrialredoxPhysiological effect

Uridine Monophosphate

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Metabolic regulationCellular protectionNeuroprotective activityLipid metabolism support

Mechanism categories

corePhysiological effectmetaboliccellular resilience

Uva Ursi

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

Valerenic Acid

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

valerenol

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Vascular function supportHPA-axis modulationNeuroprotective activityNeurotransmitter Modulation

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

Valerian Extract (Standardized)

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

Neuroprotective activityNeurotransmitter ModulationNeuroprotective Activity

Mechanism categories

corePhysiological effectnervous system

Vinpocetine

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

Metabolic regulationVascular function supportNeuroprotective activityGlucose regulation

Mechanism categories

coremetabolicPhysiological effectMetabolic modulation

Vitamin B3

Evidence: Moderate evidenceSafety: Use caution

Mechanism tags

Mitochondrial biogenesisMetabolic regulationVascular function supportLipid metabolism support

Mechanism categories

mitochondrialcorePhysiological/cellular effectPhysiological effect

Vitamin B6

Evidence: Strong evidenceSafety: Use caution

Mechanism tags

Metabolic regulationNeuroprotective activityMetabolic RegulationNeurotransmitter Modulation

Mechanism categories

corePhysiological effectmetabolicnervous system

yangonin

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityNeurotransmitter ModulationStress Response Modulation

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

Zeaxanthin

Evidence: Preliminary evidenceSafety: Use caution

Mechanism tags

AntioxidantHPA-axis modulationNeuroprotective activityOxidative Stress Modulation

Mechanism categories

corestressPhysiological effectNeuroendocrine modulation

Gastrodia

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityStress Response ModulationNeuroprotective Activity

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

Jatamansi

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityStress Response ModulationNeuroprotective Activity

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

Polygala

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityStress Response ModulationNeuroprotective Activity

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

Shankhpushpi

Evidence: Limited evidenceSafety: Use caution

Mechanism tags

HPA-axis modulationNeuroprotective activityStress Response ModulationNeuroprotective Activity

Mechanism categories

stresscoreNeuroendocrine modulationPhysiological effect

Evidence Provenance

This page summarizes goal-level comparison signals only. For entity-specific sourcing, safety notes, mechanisms, and evidence context, review the underlying compound profiles and the site methodology.

Capsicum FrutescensCanonical profile pending; no profile link is shown until a static route exists.

CayenneOpen the profile for sourcing, safety context, and mechanism notes →Citicoline / CDP-cholineOpen the profile for sourcing, safety context, and mechanism notes →Celastrus PaniculatusOpen the profile for sourcing, safety context, and mechanism notes →charantinOpen the profile for sourcing, safety context, and mechanism notes →CholineOpen the profile for sourcing, safety context, and mechanism notes →

CiticolineCanonical profile pending; no profile link is shown until a static route exists.

Review Carefully — Lavender Extract

Review Carefully — Bacopa

Thyroid conditions or anticholinergic drugs

Review Carefully — Devils Claw Extract

Review Carefully — Glycinate Magnesium Complex

Review Carefully — Iberogast

Review Carefully — Maca (Lepidium meyenii)

Review Carefully — Passionflower Extract

Review Carefully — Blueberry

Review Carefully — Hawthorn Extract

Review Carefully — Lion's Mane

Review Carefully — Huperzia Serrata

Review Carefully — L Norvaline

Review Carefully — Lion’s Mane

Known mushroom allergies

Review Carefully — Nicotiana Glauca

Review Carefully — Valerian

Review Carefully — 5-HTP

Review Carefully — acetate

Review Carefully — Acetyl-L-Carnitine

Review Carefully — Agaricus blazei

Review Carefully — Agmatine sulfate

Review Carefully — Alkylamides

Review Carefully — Allicin

Review Carefully — alpha-asarone

Review Carefully — Alpha-GPC

High baseline cardiovascular risk (TMAO context)

Review Carefully — Amanita muscaria

Review Carefully — American Ginseng Extract

Review Carefully — American Yellow Lotus

Review Carefully — anabasine

Review Carefully — anatabine

Review Carefully — Angelica Dahurica

Review Carefully — arjunolic acid

Review Carefully — Ashitaba Extract

Review Carefully — aspalathin

Review Carefully — astragaloside iv

Review Carefully — atractylenolide i

Review Carefully — atractylenolide iii

Review Carefully — Bacopa extract standardized

Review Carefully — bacopaside ii

Review Carefully — bacoside a

Review Carefully — bacoside b

Review Carefully — Beta-sitosterol

Review Carefully — Betaine

Review Carefully — beta- hydroxybutyrate

Review Carefully — Bilberry Extract

Review Carefully — bilobetin

Review Carefully — Burdock Root

Review Carefully — Caffeine

Review Carefully — caffeine l-theanine

Review Carefully — Capsicum Frutescens

Review Carefully — Cayenne

Review Carefully — Citicoline / CDP-choline

Review Carefully — Celastrus Paniculatus

Review Carefully — charantin

Review Carefully — Choline

Review Carefully — Citicoline

Review Carefully — Cnidium Monnieri

Review Carefully — vitamin b12

Review Carefully — Coconut Oil

Review Carefully — Ubiquinol CoQ10

Review Carefully — Curcumin phytosome

Review Carefully — Curcumin + piperine

Review Carefully — desmethoxyyangonin

Review Carefully — DHEA

Review Carefully — Dietary Nitrates

Review Carefully — dihydrokavain

Review Carefully — dihydromethysticin

Review Carefully — EGCG + Caffeine

Review Carefully — Estrogen Balance Stack

Review Carefully — GABA (Oral)

Review Carefully — Galantamine

Review Carefully — Ginkgo

Review Carefully — ginkgolide b

Review Carefully — Ginkgolides

Review Carefully — Glycine

Review Carefully — Glycine (Sleep Use)

Review Carefully — Graviola (Annona muricata)

Review Carefully — Guayusa

Review Carefully — gurmarin

Review Carefully — gymnemic acid

Review Carefully — Harmaline

Review Carefully — Harmine

Review Carefully — HCG Diet

Review Carefully — hericenones

Review Carefully — Huperzine A

Review Carefully — huperzine b

Review Carefully — Hyperforin

Review Carefully — Ibogaine

Review Carefully — imperatorin

Review Carefully — Iodine

Review Carefully — isoimperatorin

Review Carefully — Ketamine

Review Carefully — Kratom

Review Carefully — arginine

Review Carefully — L-theanine

Review Carefully — L-Theanine (Sleep Use)

Review Carefully — L-Tyrosine

Review Carefully — lagerstroemin

Review Carefully — Lavender

Review Carefully — Lecithin

Review Carefully — Lemon Balm Extract

Review Carefully — linalool

Review Carefully — Lithium Orotate

Review Carefully — Lobelia Inflata

Review Carefully — lobeline

Review Carefully — Lycopene

Review Carefully — Maca Root Extract

Review Carefully — magnolol

Review Carefully — Manganese

Review Carefully — Matcha

Review Carefully — methyl eugenol

Review Carefully — methyleugenol

Review Carefully — methysticin

Review Carefully — momordicoside k

Review Carefully — mulberroside a

Review Carefully — Myristica Fragrans

Review Carefully — myristicin

Review Carefully — NAC

Review Carefully — Nicotiana Tabacum

Review Carefully — nicotine

Review Carefully — Noopept

Review Carefully — Nutmeg (Myristica fragrans)

Review Carefully — Omega-3 fatty acids

Review Carefully — Omega-3 DHA-Dominant

Review Carefully — Omega-3 EPA

Review Carefully — Omega-3 EPA-Dominant

Review Carefully — Panax Ginseng Extract

Review Carefully — American Ginseng

Review Carefully — Pantethine

Review Carefully — Passionflower

Review Carefully — Passionflower Extract (Standardized)

Review Carefully — Phenylalanine

Review Carefully — Phloretin

Review Carefully — Phosphatidylcholine

Review Carefully — Black Pepper

Review Carefully — Pomegranate Extract

Review Carefully — Pregnenolone

Review Carefully — Bifidobacterium Probiotic

Review Carefully — propionate

Review Carefully — Psilocybin

Review Carefully — puerarin

Review Carefully — putrescine

Review Carefully — Pyridoxal-5-phosphate

Review Carefully — Rhodiola

Review Carefully — Rosemary

Review Carefully — safranal

Review Carefully — SAM-e

Review Carefully — serine

Review Carefully — Shilajit Extract

Review Carefully — Tanshinone IIA

Review Carefully — Taurine

Review Carefully — Testosterone Support Stack

Review Carefully — Tetrahydroharmine

Review Carefully — THCV

Review Carefully — theanine

Review Carefully — Cacao

Review Carefully — thujone

Review Carefully — timosaponin aiii

Review Carefully — trigonelline

Review Carefully — Uridine Monophosphate

Review Carefully — Uva Ursi

Review Carefully — Valerenic Acid

Review Carefully — valerenol

Review Carefully — Valerian Extract (Standardized)

Review Carefully — Vinpocetine

Review Carefully — Vitamin B3

Review Carefully — Vitamin B6

Review Carefully — yangonin

Review Carefully — Zeaxanthin

Review Carefully — Gastrodia

Review Carefully — Jatamansi

Review Carefully — Polygala

Review Carefully — Shankhpushpi

Common Reasons People Stop

Lavender Extract:
Bacopa: Mild GI cramping or fatigue
Devils Claw Extract:
Glycinate Magnesium Complex:
Iberogast:
Maca (Lepidium meyenii):
Passionflower Extract:
Blueberry:
Hawthorn Extract:
Lion's Mane:
Huperzia Serrata:
L Norvaline:
Lion’s Mane: Slow onset and subtle daily feedback
Nicotiana Glauca:
Valerian:
5-HTP:
acetate:
Acetyl-L-Carnitine:
Agaricus blazei:
Agmatine sulfate:
Alkylamides:
Allicin:
alpha-asarone:
Alpha-GPC: Brain fog if choline load is already saturated
Amanita muscaria:
American Ginseng Extract:
American Yellow Lotus:
anabasine:
anatabine:
Angelica Dahurica:
arjunolic acid:
Ashitaba Extract:
aspalathin:
astragaloside iv:
atractylenolide i:
atractylenolide iii:
Bacopa extract standardized:
bacopaside ii:
bacoside a:
bacoside b:
Beta-sitosterol:
Betaine:
beta- hydroxybutyrate:
Bilberry Extract:
bilobetin:
Burdock Root:
Caffeine:
caffeine l-theanine:
Capsicum Frutescens: Varying compliance
Cayenne:
Citicoline / CDP-choline:
Celastrus Paniculatus:
charantin:
Choline:
Citicoline: Varying compliance
Cnidium Monnieri:
vitamin b12:
Coconut Oil:
Ubiquinol CoQ10:
Curcumin phytosome:
Curcumin + piperine:
desmethoxyyangonin:
DHEA:
Dietary Nitrates:
dihydrokavain:
dihydromethysticin:
EGCG + Caffeine:
Estrogen Balance Stack:
GABA (Oral):
Galantamine:
Ginkgo:
ginkgolide b:
Ginkgolides:
Glycine:
Glycine (Sleep Use):
Graviola (Annona muricata):
Guayusa:
gurmarin:
gymnemic acid:
Harmaline:
Harmine:
HCG Diet:
hericenones:
Huperzine A:
huperzine b:
Hyperforin:
Ibogaine:
imperatorin:
Iodine:
isoimperatorin:
Ketamine:
Kratom:
arginine:
L-theanine:
L-Theanine (Sleep Use):
L-Tyrosine:
lagerstroemin:
Lavender:
Lecithin:
Lemon Balm Extract:
linalool:
Lithium Orotate:
Lobelia Inflata:
lobeline:
Lycopene:
Maca Root Extract:
magnolol:
Manganese:
Matcha:
methyl eugenol:
methyleugenol:
methysticin:
momordicoside k:
mulberroside a:
Myristica Fragrans:
myristicin:
NAC:
Nicotiana Tabacum:
nicotine:
Noopept:
Nutmeg (Myristica fragrans):
Omega-3 fatty acids:
Omega-3 DHA-Dominant:
Omega-3 EPA:
Omega-3 EPA-Dominant:
Panax Ginseng Extract:
American Ginseng:
Pantethine:
Passionflower:
Passionflower Extract (Standardized):
Phenylalanine:
Phloretin:
Phosphatidylcholine:
Black Pepper:
Pomegranate Extract:
Pregnenolone:
Bifidobacterium Probiotic:
propionate:
Psilocybin:
puerarin:
putrescine:
Pyridoxal-5-phosphate:
Rhodiola:
Rosemary:
safranal:
SAM-e:
serine:
Shilajit Extract:
Tanshinone IIA:
Taurine:
Testosterone Support Stack:
Tetrahydroharmine:
THCV:
theanine:
Cacao:
thujone:
timosaponin aiii:
trigonelline:
Uridine Monophosphate:
Uva Ursi:
Valerenic Acid:
valerenol:
Valerian Extract (Standardized):
Vinpocetine:
Vitamin B3:
Vitamin B6:
yangonin:
Zeaxanthin:
Gastrodia:
Jatamansi:
Polygala:
Shankhpushpi:

Commonly Discussed Forms

Lavender Extract: Standard form
Bacopa: Standardized bacosides extract
Devils Claw Extract: Standard form
Glycinate Magnesium Complex: Standard form
Iberogast: Standard form
Maca (Lepidium meyenii): Standard form
Passionflower Extract: Standard form
Blueberry: Standard form
Hawthorn Extract: Standard form
Lion's Mane: Standard form
Huperzia Serrata: Standard form
L Norvaline: Standard form
Lion’s Mane: Fruiting body extract or mycelium biomass
Nicotiana Glauca: Standard form
Valerian: Standard form
5-HTP: Standard form
acetate: Standard form
Acetyl-L-Carnitine: Standard form
Agaricus blazei: Standard form
Agmatine sulfate: Standard form
Alkylamides: Standard form
Allicin: Standard form
alpha-asarone: Standard form
Alpha-GPC: Choline alphoscerate powder or capsules
Amanita muscaria: Standard form
American Ginseng Extract: Standard form
American Yellow Lotus: Standard form
anabasine: Standard form
anatabine: Standard form
Angelica Dahurica: Standard form
arjunolic acid: Standard form
Ashitaba Extract: Standard form
aspalathin: Standard form
astragaloside iv: Standard form
atractylenolide i: Standard form
atractylenolide iii: Standard form
Bacopa extract standardized: Standard form
bacopaside ii: Standard form
bacoside a: Standard form
bacoside b: Standard form
Beta-sitosterol: Standard form
Betaine: Standard form
beta- hydroxybutyrate: Standard form
Bilberry Extract: Standard form
bilobetin: Standard form
Burdock Root: Standard form
Caffeine: Standard form
caffeine l-theanine: Standard form
Capsicum Frutescens: Standard form
Cayenne: Standard form
Citicoline / CDP-choline: Standard form
Celastrus Paniculatus: Standard form
charantin: Standard form
Choline: Standard form
Citicoline: Standard form
Cnidium Monnieri: Standard form
vitamin b12: Standard form
Coconut Oil: Standard form
Ubiquinol CoQ10: Standard form
Curcumin phytosome: Standard form
Curcumin + piperine: Standard form
desmethoxyyangonin: Standard form
DHEA: Standard form
Dietary Nitrates: Standard form
dihydrokavain: Standard form
dihydromethysticin: Standard form
EGCG + Caffeine: Standard form
Estrogen Balance Stack: Standard form
GABA (Oral): Standard form
Galantamine: Standard form
Ginkgo: Standard form
ginkgolide b: Standard form
Ginkgolides: Standard form
Glycine: Standard form
Glycine (Sleep Use): Standard form
Graviola (Annona muricata): Standard form
Guayusa: Standard form
gurmarin: Standard form
gymnemic acid: Standard form
Harmaline: Standard form
Harmine: Standard form
HCG Diet: Standard form
hericenones: Standard form
Huperzine A: Standard form
huperzine b: Standard form
Hyperforin: Standard form
Ibogaine: Standard form
imperatorin: Standard form
Iodine: Standard form
isoimperatorin: Standard form
Ketamine: Standard form
Kratom: Standard form
arginine: Standard form
L-theanine: Standard form
L-Theanine (Sleep Use): Standard form
L-Tyrosine: Standard form
lagerstroemin: Standard form
Lavender: Standard form
Lecithin: Standard form
Lemon Balm Extract: Standard form
linalool: Standard form
Lithium Orotate: Standard form
Lobelia Inflata: Standard form
lobeline: Standard form
Lycopene: Standard form
Maca Root Extract: Standard form
magnolol: Standard form
Manganese: Standard form
Matcha: Standard form
methyl eugenol: Standard form
methyleugenol: Standard form
methysticin: Standard form
momordicoside k: Standard form
mulberroside a: Standard form
Myristica Fragrans: Standard form
myristicin: Standard form
NAC: Standard form
Nicotiana Tabacum: Standard form
nicotine: Standard form
Noopept: Standard form
Nutmeg (Myristica fragrans): Standard form
Omega-3 fatty acids: Standard form
Omega-3 DHA-Dominant: Standard form
Omega-3 EPA: Standard form
Omega-3 EPA-Dominant: Standard form
Panax Ginseng Extract: Standard form
American Ginseng: Standard form
Pantethine: Standard form
Passionflower: Standard form
Passionflower Extract (Standardized): Standard form
Phenylalanine: Standard form
Phloretin: Standard form
Phosphatidylcholine: Standard form
Black Pepper: Standard form
Pomegranate Extract: Standard form
Pregnenolone: Standard form
Bifidobacterium Probiotic: Standard form
propionate: Standard form
Psilocybin: Standard form
puerarin: Standard form
putrescine: Standard form
Pyridoxal-5-phosphate: Standard form
Rhodiola: Standard form
Rosemary: Standard form
safranal: Standard form
SAM-e: Standard form
serine: Standard form
Shilajit Extract: Standard form
Tanshinone IIA: Standard form
Taurine: Standard form
Testosterone Support Stack: Standard form
Tetrahydroharmine: Standard form
THCV: Standard form
theanine: Standard form
Cacao: Standard form
thujone: Standard form
timosaponin aiii: Standard form
trigonelline: Standard form
Uridine Monophosphate: Standard form
Uva Ursi: Standard form
Valerenic Acid: Standard form
valerenol: Standard form
Valerian Extract (Standardized): Standard form
Vinpocetine: Standard form
Vitamin B3: Standard form
Vitamin B6: Standard form
yangonin: Standard form
Zeaxanthin: Standard form
Gastrodia: Standard form
Jatamansi: Standard form
Polygala: Standard form
Shankhpushpi: Standard form