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Guides, comparisons & explainers

Evidence Library

Guides, articles, mental health explainers, comparisons, and science foundations — organized as one connected library instead of separate content silos.

Compare the evidence

Compare botanicals across anxiety, sleep, and focus goals

Use the Botanical Activity Atlas to filter the same structured library by calming, sleep-related, stimulating, cognition, chemistry, evidence strength, noticeability, and safety signals. It is the fastest way to compare options before opening individual guides.

High-signal evidence guide

Best Natural Sleep Aids That Work

A 22-source clinical ledger that separates chronic-insomnia treatment from supplement evidence and ranks melatonin, L-theanine, magnesium, ashwagandha, valerian, passionflower, and glycine conservatively.

Read the sleep evidence guide

New evidence cluster

Substance Use, Dependence & Harm Reduction

One hub for mitragynine, 7-OH, MGM-15, mitragynine pseudoindoxyl, corynoxine B, tianeptine, withdrawal evidence, novel psychoactives, and risk-reduction research.

Explore the substance-use evidence hub

Browse by subject

Choose the question you are trying to answer.

Mental Health

OCD, BPD, and every named DSM-5-TR personality disorder — citation-rich guides covering diagnosis, differential diagnosis, treatment, safety, and stigma.

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Substance Use & Harm Reduction

Dependence, withdrawal, overdose risk, kratom-derived opioids, tianeptine, emerging psychoactives, and harm-reduction evidence — with uncertainty kept explicit.

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ADHD

Supplements, nutrients, and strategies for attention and executive function — 22 evidence-based guides.

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Sleep

Natural sleep aids, melatonin alternatives, and sleep hygiene — 17 guides with clinical evidence.

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Stress

Evidence-aware guides for acute tension, chronic overload, burnout, adaptogens, and stress-support decisions.

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Anxiety

Evidence-graded guides for anxious thoughts, physical tension, and calm — with safety warnings kept visible.

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Focus & Cognition

Nootropics, focus stacks, and cognitive enhancement — 6 guides on getting more from your brain.

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Metabolic Health

Blood sugar, insulin sensitivity, weight-loss claims, medication context, and metabolic supplement comparisons kept tied to human evidence.

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Herb Guides

Deep-dive monographs on individual herbs — ashwagandha, kava, passionflower, rhodiola, turmeric.

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Comparisons

Head-to-head supplement comparisons — ashwagandha vs rhodiola, melatonin vs valerian, and more.

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Best Supplements

Curated recommendations for specific needs — blood pressure, fat loss, joint support, gut health.

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Science Foundations

Research literacy, neuroscience, interactions, and product quality explainers that make the rest of the library easier to evaluate.

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Supplement Topic Guides

Form and quality guides, popular supplement categories, goal-based routines, advanced compounds, and harm reduction — organized by the decision you are making.

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Structured reference

Browse the reference databases

Prefer structured profiles? Browse the published herb and compound libraries, where public eligibility rules keep source inventory separate from what readers can actually browse.