Evidence-gated safety content
Only editorially approved combinations with meaningful supporting evidence are published here. Arbitrary Safety Checker combinations remain dynamic screening results and are not turned into indexable pages.
documented · higher confidence
Evidence-focused review of the documented interaction between St. John's wort and hormonal contraceptives, including CYP3A-related pharmacokinetic evidence.
Read interaction evidence →documented · moderate confidence
Evidence-focused review of St. John's wort with serotonergic antidepressants, separating pharmacodynamic serotonin concerns from drug-metabolism effects.
Read interaction evidence →