Related Compounds
Compounds connected by the same goals, effects, or research topics.
Compound Profile
Shilajit
Shilajit carries a Grade C rating — limited evidence.
Review needed — heavy metal contamination risk; limited safety data Details
Last reviewed: •1 source citedReport a correctionProfile-wide ·C Limited
At a glance
From this profile's structured data- Evidence
- Grade C
- Safety
- heavy metal contamination risk; limited safety data
- Profile context
- mitochondrial pathways proposed
Quick stats
- Evidence level
- Limited evidence
- Typical onset
- Varies by prep
- Safety rating
- Review needed: Limited safety data
- Best for
- Mitochondrial Pathways Proposed
Safety
Safety & Cautions
heavy metal contamination risk; limited safety data
Elevated caution
Caution level: Elevated. One caution category applies — read it before use.
- Hormonal Activity ContextHormone-adjacent wording is present and should be interpreted carefully.
Evidence Summary
Profile-wide ·C LimitedEvidence lens
Read as directional context, not settled clinical proof.
LimitedLimited evidence
Human clinical evidence: Present in source signals
Mechanistic / preclinical: Mechanism mapped — Mitochondrial Support · Endocrine · Mitochondrial
Research maturity: Emerging research — main contexts: Mitochondrial Pathways Proposed
Safety boundary: Safety note available — heavy metal contamination risk; limited safety data
This profile cites 1 human study.
Evidence Strength
Confidence estimate based on the design quality and consistency of published clinical trials.
Shilajit has a limited evidence rating.
General wellnessGeneral wellness
Citation density
1.0
Sources
1
Effects
1
Research recency
Mixed recency
Evidence Grade
Grade C: Limited Evidence
Evaluation of methodological rigor, population reach, and evidence alignment.
- Design Match
- Randomized controlled trial
- Risk of Bias
- Low
- Consistency
- Not assessed
Strongest recorded design is a randomized controlled trial, drawn from 2 recorded studies, 2 in people.
How evidence grades work
Each grade reflects the strength and consistency of published human evidence — not marketing claims. Grades are based on study count, design quality, effect size, consistency, and recency.
- Strong
- Multiple RCTs, consistent direction, adequate effect size
- Moderate
- Some RCTs or consistent observational data in humans
- Preliminary / Mixed
- Animal or in-vitro only, or conflicting human data
- Traditional / Theoretical
- Traditional use only; no controlled human trials
Clinical Study Summaries (1)1 human evidence source · 1 human trial · Participant totals not consistently reported · Consistency not yet classifiable
What the evidence actually shows
This table contains 1 structured source, including 1 human evidence source; 1 is a human trial.
| Study | Design | N | Dose | Duration | Population | Outcome | Result & magnitude | Source |
|---|---|---|---|---|---|---|---|---|
Clinical evaluation of purified Shilajit on testosterone levels in healthy volunteers PubMed · Andrologia · 2016 Background | Randomized controlled trial Randomly assigns participants to interventions or controls, reducing many sources of bias when the trial is conducted well. | — | — | — | — | — | — | PubMed → |
How Shilajit Works
Simplified mechanism pathway based on preclinical and pharmacological evidence. Does not confirm clinical efficacy.
Mechanism Pathway — How Shilajit Works
CompoundTarget / ReceptorMechanismEffect / Outcome
Dosing
- Common form
- chelated mineral capsule or powder
- No standardized dose
- Our source data records the usual product form for this ingredient but no studied dose. Preparations differ widely, so follow the standardization on the product you actually have and speak to a clinician before starting.
Mechanisms & biological pathways
Preclinical mechanism details from scientific profiles; these represent plausible pathways but do not guarantee clinical efficacy in humans.
- Mitochondrial Support
- Endocrine
- Mitochondrial
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Compare & Sourcing
Compare side-by-side tradeoffs or verify active marker guidelines.
Review available sources for Shilajit
Independent database mapping — evaluated separately from safety and efficacy scores.
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Safety first · Harm reduction
This information is educational and not medical advice. Start low, avoid risky combinations, and consult a licensed clinician before making health decisions—especially if you use medications, have diagnosed conditions, or are pregnant/breastfeeding.
Learn how we evaluate confidence, safety, and intensity on the methodology page.
Editorial Review
Checked against primary sources, cited evidence, and contraindication language before publication. Evidence claims, safety language, and affiliate modules are reviewed independently. Not personal medical advice.
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