We use privacy-friendly analytics. Read our privacy policy.

Compound Profile

Lavender Extract

Lavender Extract is best framed as a conservative research profile with mechanistic evidence and a focus on Sleep; Stress Response; Neurobiology.

Use extra caution — GI upset and sedation possible; caution with CNS depressants. Details

Last reviewed: •2 sources citedReport a correctionProfile-wide ·D Preliminary
Lavender Extract monograph visual
Generated profile category visual

At a glance

From this profile's structured data
Evidence
Grade D
Safety
GI upset and sedation possible; caution with CNS depressants.
Profile context
voltage-gated calcium channels, serotonin signaling
Next steps

Continue reading

Quick stats

Evidence level
Preliminary evidence
Typical onset
Varies by prep
Safety rating
Use extra caution: Use caution
Best for
Voltage Gated Calcium Channels, Serotonin Signaling
Avoid / review if
Known Allergy To Lavender Or Other Lamiaceae/Mint Family Plants, Pregnancy Or Breastfeeding Without Clinician Guidance For Oral Lavender Oil Preparations

Safety

Safety & Cautions

GI upset and sedation possible; caution with CNS depressants.

High caution

Caution level: High. Multiple caution categories apply, or the record uses avoid/contraindication language.

  • Hormonal Activity ContextHormone-adjacent wording is present and should be interpreted carefully.
  • Pregnancy/Breastfeeding CautionPregnancy or breastfeeding caution language is present.

Evidence-based safety

Caution when combined

Severity and certainty are shown separately. A high-priority caution can still be theoretical: these pairings are screened from shared contraindication mechanisms and are not automatically documented clinical interactions. Provenance identifies the source fields that produced each flag; it does not upgrade the certainty of the pairwise claim.

Evidence Summary

Profile-wide ·D Preliminary

Evidence lens

Early signal that needs stronger human replication before practical claims.

PreliminaryPreliminary evidence

Human clinical evidence: Present in source signals

Mechanistic / preclinical: Mechanism mapped — Neurotransmitter Modulation · Stress Response Modulation · Serotonergic

Research maturity: Preliminary research — Early findings are not treated as established consumer benefit.

Safety boundary: Safety note available — GI upset and sedation possible; caution with CNS depressants.

This profile cites 2 human studies.

Evidence Strength

Confidence estimate based on the design quality and consistency of published clinical trials.

Preliminary evidence

Lavender Extract has a preliminary evidence rating.

AdaptogenSleepFocusStress & Mood
Citation density
1.0
Sources
2
Effects
2
Research recency
Mixed recency
Evidence Grade

Grade D: Preliminary / Theoretical Evidence

Evaluation of methodological rigor, population reach, and evidence alignment.

Design Match
Randomized controlled trial
Risk of Bias
Low
Consistency
Consistent
Strongest recorded design is a randomized controlled trial, drawn from 4 recorded studies, 3 in people. No disagreement is recorded across them.
How evidence grades work

Each grade reflects the strength and consistency of published human evidence — not marketing claims. Grades are based on study count, design quality, effect size, consistency, and recency.

Strong
Multiple RCTs, consistent direction, adequate effect size
Moderate
Some RCTs or consistent observational data in humans
Preliminary / Mixed
Animal or in-vitro only, or conflicting human data
Traditional / Theoretical
Traditional use only; no controlled human trials
Clinical Study Summaries (2)1 human evidence source · 1 human trial · ~539 participants across 1 human evidence source with reported N · Consistency not yet classifiable

Filter by study class

Showing 2 of 2 studies.

What the evidence actually shows

This table contains 2 structured sources, including 1 human evidence source; 1 is a human trial. Across 1 human evidence source with a reported sample size, the approximate participant total is 539; overlapping publications may include some of the same people.

StudyDesignNDoseDurationPopulationOutcomeResult & magnitudeSource

Lavender oil preparation Silexan is effective in generalized anxiety disorder--a randomized, double-blind comparison to placebo and paroxetine

PubMed · Int J Neuropsychopharmacol · 2014

Background
Randomized controlled trial

Randomly assigns participants to interventions or controls, reducing many sources of bias when the trial is conducted well.

n=539—————PubMed →

Efficacy and safety of silexan, a new, orally administered lavender oil preparation, in subthreshold anxiety disorder - evidence from clinical trials

PubMed · Wien Med Wochenschr · 2010

Background
Narrative review

Summarizes selected literature without the full prespecified search and selection methods of a systematic review.

——————PubMed →

How Lavender Extract Works

Simplified mechanism pathway based on preclinical and pharmacological evidence. Does not confirm clinical efficacy.

Mechanism Pathway — How Lavender Extract Works

How Lavender Extract WorksLavender Extract acts on biological target pathways via neurotransmitter (modulation), leading to voltage gated calcium channels.Lavender ExtractBiological TargetBiological pathwayNeurotransmitterModulationVoltage Gated Calcium ChannelsObservable outcomeHPA AxisModulation
CompoundTarget / ReceptorMechanismEffect / Outcome

Dosing

Common form
oral lavender oil
No standardized dose
Our source data records the usual product form for this ingredient but no studied dose. Preparations differ widely, so follow the standardization on the product you actually have and speak to a clinician before starting.
Mechanisms & biological pathways

Preclinical mechanism details from scientific profiles; these represent plausible pathways but do not guarantee clinical efficacy in humans.

  • Neurotransmitter Modulation
  • Stress Response Modulation
  • Serotonergic
  • Anxiolytic

Guides that use Lavender Extract

Continue exploring

Related research paths

Compare & Sourcing

Compare side-by-side tradeoffs or verify active marker guidelines.

Free safety checklist

Get the Lavender Extract evidence notes

Occasional research updates, safety context, and product-quality checks for supplement decisions.

We use your email to send the checklist and occasional evidence-first supplement updates. Unsubscribe anytime. Privacy policy.

Safety first · Harm reduction

This information is educational and not medical advice. Start low, avoid risky combinations, and consult a licensed clinician before making health decisions—especially if you use medications, have diagnosed conditions, or are pregnant/breastfeeding.

Learn how we evaluate confidence, safety, and intensity on the methodology page.

Editorial Review

Checked against primary sources, cited evidence, and contraindication language before publication. Evidence claims, safety language, and affiliate modules are reviewed independently. Not personal medical advice.

Editorial Standards →

Help improve this profile

Was this useful for your research?

These controls record only the page and the structured choice you make when analytics consent is enabled. Please don’t include personal medical information in research requests.

Was this evidence summary clear?

Did you find what you were researching?