Herb Profile

Chamomile

Chamomile may support mild anxiety or sleep quality, especially as evening tea or standardized extract.

Last reviewed: July 9, 2026•7 human studies cited

B Moderate

Use extra caution — May support sleep quality and calm/anxiety symptoms; evidence is supportive but not definitive. Details

Evidence: Moderate Human Evidence
Typical onset: Varies by prep
Safety rating: Moderate caution
Best for: Sleep, Stress
Avoid / review if: Anticoagulants (Coumarin Content)

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Chamomile

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Where to go next — guides & comparisons

If you want help sleeping → Sleep guides
If you want help with anxiety or stress → Anxiety & stress guides
If you want to browse more herbs → All herbs

Safety & Cautions

May support sleep quality and calm/anxiety symptoms; evidence is supportive but not definitive. | Do not claim it treats insomnia or anxiety disorders; do not imply sleep duration/efficiency improvements are consistent.

60%

Moderate caution — review before use

Detailed safety fields

Pregnancy, breastfeeding, and contraindications

- Anticoagulants (Coumarin Content)

Safety classifications

- Stimulant-Like Profile: Stimulant-like or activating caution language is present.

Full safety note

- May support sleep quality and calm/anxiety symptoms; evidence is supportive but not definitive. | Do not claim it treats insomnia or anxiety disorders; do not imply sleep duration/efficiency improvements are consistent. | Use as beginner friendly sleep/anxiety page with allergy and objective evidence caveats.

Safety labels

- Stimulant-Like Profile

Evidence-based safety

Caution when combined

These pairings share a flagged risk mechanism. They are additive-effect cautions derived from contraindication data, not confirmed clinical interactions. Consult a clinician before combining.

High-Priority Caution

147 flagged pairings

Bleeding / anticoagulant risk

Browse the grouped cautions below. The list scrolls inside this card when long.

Bleeding / anticoagulant risk

Evidence Summary

Evidence lens

Useful signal, but study design, dose, and population still matter.

ModerateModerate Human Evidence

Human clinical evidence: Present in source signals

Mechanistic / preclinical: Mechanism mapped — Stress Response Modulation

Research maturity: More interpretable — Long Term Human Evidence May Be Limited.

Safety boundary: Safety note available — May support sleep quality and calm/anxiety symptoms; evidence is supportive but not definitive.

This profile cites 7 human studies.

How evidence grades work

Each grade reflects the strength and consistency of published human evidence — not marketing claims. Grades are based on study count, design quality, effect size, consistency, and recency.

Strong

Multiple RCTs, consistent direction, adequate effect size

Moderate

Some RCTs or consistent observational data in humans

Preliminary / Mixed

Animal or in-vitro only, or conflicting human data

Traditional / Theoretical

Traditional use only; no controlled human trials

Clinical Study Summaries (5)Cited studies informing this profile. RCTs and reviews shown first.

Study	Type	Sample	Source
The Effect of Oral Chamomile on Anxiety: A Systematic Review of Clinical Trials Sogand Saadatmand; Foad Zohroudi; Hadith Tangestani (2024)	Systematic review	—	Source →
Effects of chamomile (Matricaria chamomilla L.) on sleep: A systematic review and meta-analysis of clinical trials Asma Kazemi; S. Shojaei-Zarghani; Parham Eskandarzadeh; Mohammad Hashem Hashempur (2024)	Meta-analysis	—	Source →
Warfarin and food, herbal or dietary supplement interactions: A systematic review Tan CSS et al. (2021)	—	—	PubMed →
Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils Lin TK et al. (2017)	—	—	PubMed →
Chamomile: A Review of Its Traditional Uses, Chemical Constituents, Pharmacological Activities and Quality Control Studies Dai YL et al. (2022)	—	—	PubMed →

Dosing & Timing

Dose guidance

Dose/form varies widely across tea, extract, capsule, and inhalation studies. Use source specific dose when known. | Oral chamomile and chamomile preparations; aromatherapy evidence is separate and should not be merged with oral extract/tea.

How Chamomile Works

Simplified mechanism pathway based on preclinical and pharmacological evidence. Does not confirm clinical efficacy.

Mechanism Pathway — How Chamomile Works

CompoundTarget / ReceptorMechanismEffect / Outcome

Mechanisms & Biological Pathways

Preclinical pathways

Proposed mechanisms from in vitro and animal research; these do not confirm clinical outcomes in humans.

Stress Response Modulation

Active Compounds

Key constituents studied in Chamomile, with full pharmacology and safety profiles.

Condition guides

Anxiety Recovery Sleep Stress Blood pressure

Compare & Sourcing

Compare side-by-side tradeoffs or verify active marker guidelines.

Review available sources for Chamomile

Independent database mapping — evaluated separately from safety and efficacy scores.

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Safety first · Harm reduction

This information is educational and not medical advice. Start low, avoid risky combinations, and consult a licensed clinician before making health decisions—especially if you use medications, have diagnosed conditions, or are pregnant/breastfeeding.

Learn how we evaluate confidence, safety, and intensity on the methodology page.

Editorial Review

Checked against primary sources, cited evidence, and contraindication language before publication. Evidence claims, safety language, and affiliate modules are reviewed independently. Not personal medical advice.

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Botanical profile context

How to interpret Chamomile

Chamomile dosage ranges, effects, drug interactions, and harm-reduction safety guide for sleep. Moderate Human Evidence research evidence. Use this herb profile as a starting point for evidence review, not as a recommendation to start a new supplement. Botanical products can vary by plant part, extract ratio, standardization, dose, and contaminant testing, so two labels with the same common name may not behave the same way.

When reviewing Chamomile, compare the traditional-use context against the human evidence, mechanism notes, and safety cautions. Pay special attention to pregnancy, breastfeeding, liver or kidney disease, blood-pressure effects, sedation, stimulation, anticoagulant use, antidepressants, and any prescription medication overlap.

For product decisions, prefer transparent labels, named extracts, clear serving sizes, and third-party quality testing. Avoid treating a long list of possible mechanisms as proof that an herb will solve a specific condition.