Compound Profile

Lavender

Lavender is best framed as a calming botanical with moderate human evidence for anxiety support and relaxation, especially for oral lavender oil preparations, while sleep and aromatherapy claims should stay conservative.

Last reviewed: 2 human studies cited

B Moderate

Monograph visual

Lavender

Generated profile category visual

Verdict: LavenderMaybe

Best for

  • Mild-to-moderate everyday anxiety
  • Restlessness with a low-risk profile

Not ideal for

  • Panic or severe anxiety
  • A reliable sleep sedative on its own
Evidence confidence
Moderate — standardized oral preparations have real trial support
Expected onset
1–2 weeks
Give it
4–6 weeks
Bottom line: Standardized oral lavender has surprisingly solid trials for mild anxiety and is well tolerated. Aromatherapy effects are gentler and less consistent.

On the evidence: Randomized trials of standardized oral lavender show anxiolytic effects comparable to low-dose reference agents.

How strong is the evidence?Moderate

Why not higher

  • The good evidence is for one standardized oral preparation, not lavender generally
  • Aromatherapy evidence is much weaker
  • Most trials are short

Why not lower

  • Randomized trials show a real anxiolytic effect for standardized oral lavender
  • It is well tolerated with a low-risk profile

Practical takeaway: A reasonable low-risk option for mild everyday anxiety if you use a standardized oral product. Not a substitute for care in severe anxiety.

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Quick Stats

Evidence level

Moderate evidence

Typical onset

Varies by prep

Safety rating

Use extra caution: Safety review pending

Best for

GABA A, Autonomic Nervous System

Avoid / review if

Known Allergy To Lavender Or Other Lamiaceae/Mint Family Plants, Pregnancy Or Breastfeeding Without Clinician Guidance For Oral Lavender Oil Preparations

Safety & Cautions

Review before use if any apply: Known Allergy To Lavender Or Other Lamiaceae/Mint Family Plants, Pregnancy Or Breastfeeding Without Clinician Guidance For Oral Lavender Oil Preparations.

Evidence-based safety

Caution when combined

These pairings share a flagged risk mechanism. They are additive-effect cautions derived from contraindication data, not confirmed clinical interactions. Consult a clinician before combining.

Evidence Summary

B Moderate

Evidence lens

Useful signal, but study design, dose, and population still matter.

ModerateModerate evidence

Human clinical evidence: Present in source signals

Mechanistic / preclinical: Mechanism mappedNeurotransmitter Modulation · Stress Response Modulation · Neuroprotective Activity

Research maturity: More interpretablemain contexts: GABA A · Autonomic Nervous System

Safety boundary: Safety note availableReview before use if any apply: Known Allergy To Lavender Or Other Lamiaceae/Mint Family Plants, Pregnancy Or Breastfeeding Without Clinician Guidance For Oral Lavender Oil Preparations.

This profile cites 2 human studies.

Evidence Strength

Confidence estimate based on the design quality and consistency of published clinical trials.

Moderate evidence

Lavender has a moderate evidence evidence rating.

AdaptogenSleepStress & Mood
Citation density
1.0
Sources
2
Effects
2
Research recency
Mixed recency
How evidence grades work

Each grade reflects the strength and consistency of published human evidence — not marketing claims. Grades are based on study count, design quality, effect size, consistency, and recency.

A

Strong

Multiple RCTs, consistent direction, adequate effect size

B

Moderate

Some RCTs or consistent observational data in humans

C

Preliminary / Mixed

Animal or in-vitro only, or conflicting human data

D

Traditional / Theoretical

Traditional use only; no controlled human trials

Clinical Study Summaries (2)Cited studies informing this profile. RCTs and reviews shown first.
StudyTypeSampleSource

PubMed PMID 24456909. Minimal citation row added from existing workbook PMID; title/year/journal still require PubMed metadata extraction.

PubMed

PubMed

Requires manual source normalization to PMID, DOI, PMC, or authoritative URL.

How Lavender Works

Simplified mechanism pathway based on preclinical and pharmacological evidence. Does not confirm clinical efficacy.

Mechanism Pathway — How Lavender Works

How Lavender WorksLavender acts on pathways via hpa axis (modulation), leading to gaba a.LavenderBiological pathwayHPA AxisModulationGaba AObservable outcomeNeuroprotectiveActivity
CompoundTarget / ReceptorMechanismEffect / Outcome
Mechanisms & Biological Pathways

Preclinical mechanism details from scientific profiles; these represent plausible pathways but do not guarantee clinical efficacy in humans.

Neurotransmitter ModulationStress Response ModulationNeuroprotective ActivityNeuroprotective

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Related research paths

Compare & Sourcing

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Review available sources for Lavender

Independent database mapping — evaluated separately from safety and efficacy scores.

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Safety first · Harm reduction

This information is educational and not medical advice. Start low, avoid risky combinations, and consult a licensed clinician before making health decisions—especially if you use medications, have diagnosed conditions, or are pregnant/breastfeeding.

Learn how we evaluate confidence, safety, and intensity on the methodology page.

Editorial Review

Checked against primary sources, cited evidence, and contraindication language before publication. Evidence claims, safety language, and affiliate modules are reviewed independently. Not personal medical advice.

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Compound profile context

How to interpret Lavender

Lavender dosage by use case, onset and duration, safety limits, and interactions for gaba a, graded against research. Moderate Human Evidence research evidence. Use this compound profile to understand mechanism, evidence quality, and practical safety context before comparing products or building a stack. A biochemical pathway connection can be useful for discovery, but it is not the same as proven benefit in humans.

When reviewing Lavender, separate the active molecule from the product category around it. Dose form, absorption, extract standardization, medication interactions, and individual sensitivity can change the real-world risk-benefit picture.

For supplement planning, avoid combining multiple compounds with overlapping sedating, stimulating, serotonergic, blood-pressure, anticoagulant, or liver-metabolism effects unless a qualified clinician has reviewed the context.