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Research comparison tool
One evidence matrix and eight safety-focused screening views built from the same canonical ingredient records and research-quality topology. Compare what is mapped, how many underlying human studies are represented, where evidence is stronger, and which safety signals deserve deeper review—without converting a database flag into medical advice.
The profile grade and underlying human-study count are displayed independently from outcome mappings and safety flags. Multiple publications are collapsed only when explicit trial, cohort, dataset, or parent-study identity proves they are not independent evidence.
A structured caution does not by itself establish severity, dose dependence, or a documented clinical interaction.
An empty field means the dataset does not currently contain that signal. It is never translated into a claim of no risk.
Matrix explorer
Each matrix is generated from the same canonical runtime records and research-quality topology so evidence, study counts, outcome mappings, and safety labels do not drift between tools.
Popular supplement evidence
Compare popular and high-signal research records across common outcome families. “Mapped” means the canonical profile explicitly associates that ingredient with the outcome family. The profile evidence grade is shown separately and must not be read as an outcome-specific grade.
| Ingredient | Profile evidence | Underlying human studies | Sleep / calming | Cognition / focus | Energy / stimulation | Mood | Metabolic |
|---|---|---|---|---|---|---|---|
| Ashwagandha (Withania somnifera) herb | A | 1 | Mapped | — | — | — | — |
| Magnesium compound | B | — | — | — | — | — | — |
| Melatonin compound | A | — | — | — | — | — | — |
| L-theanine compound | B | 1 | — | — | — | — | — |
| Creatine compound | D | 2 | — | — | — | — | — |
| Berberine compound | A | 2 | — | — | — | — | Mapped |
| Rhodiola herb | C | 3 | Mapped | — | Mapped | — | — |
| Saffron herb | C | 1 | Mapped | — | — | Mapped | — |
| Lion's Mane herb | D | 1 | — | Mapped | — | Mapped | — |
| Bacopa herb | A | 1 | — | Mapped | — | — | — |
| Valeriana officinalis herb | B | — | Mapped | — | — | — | — |
| Chamomile compound | D | 1 | — | — | — | — | — |
| Turmeric (Curcuma longa) herb | B | 1 | — | — | — | — | — |
| Curcumin herb | A | 1 | — | — | — | — | — |
| Omega-3 fatty acids compound | A | 1 | — | — | — | — | Mapped |
| Caffeine compound | B | — | — | — | — | — | — |
| Citicoline compound | C | — | — | Mapped | — | — | — |
| Alpha-GPC compound | D | — | — | Mapped | — | — | — |
| Inositol compound | Unassigned | — | — | — | — | — | Mapped |
| St. John's Wort (Hypericum perforatum) herb | Unassigned | — | Mapped | — | — | Mapped | — |
| Lion's Mane herb | C | 3 | — | Mapped | — | — | — |
| Vitamin B6 compound | C | 2 | — | — | — | — | Mapped |
| Iron compound | A | 1 | — | — | — | — | — |
| Boswellia compound | B | 1 | — | — | — | — | — |
| caffeine l-theanine compound | B | 1 | — | — | — | — | — |
| Carnitine L Tartrate compound | B | 1 | Mapped | — | — | — | Mapped |
| Garlic (Allium sativum) herb | B | 1 | — | — | — | — | — |
| Ginger (Zingiber officinale) herb | B | 1 | — | — | — | Mapped | — |
| Green Tea Extract herb | B | 1 | — | — | — | — | Mapped |
| Lavender compound | B | 1 | — | — | — | — | — |
| Milk Thistle (Silybum marianum) herb | B | 1 | — | — | — | — | — |
| Passionflower herb | B | 1 | Mapped | — | — | — | — |
| Saffron Extract compound | B | 1 | Mapped | — | — | — | Mapped |
| Saw Palmetto (Serenoa repens) herb | B | 1 | — | — | — | — | — |
| Saw Palmetto Extract compound | B | 1 | — | — | — | — | Mapped |
| Taurine compound | B | 1 | — | — | — | — | — |
| Tribulus (Tribulus terrestris) herb | B | 1 | Mapped | — | — | — | — |
| Valerian herb | B | 1 | Mapped | — | — | — | — |
| Willow Bark Extract compound | B | 1 | Mapped | — | — | — | — |
| 11-keto-beta-boswellic acid compound | C | 1 | — | — | — | — | — |
| 23-epi-26-deoxyactein compound | C | 1 | — | — | — | — | — |
| Acarbose compound | C | 1 | — | — | — | — | Mapped |
| Acerola herb | C | 1 | — | — | — | — | — |
| Andrographis Paniculata herb | C | 1 | — | — | — | — | — |
| Banaba Leaf Extract compound | C | 1 | Mapped | — | — | — | Mapped |
| Bitter Melon herb | C | 1 | — | — | — | — | Mapped |
| Carob herb | C | 1 | — | — | — | — | Mapped |
| Citrus Sinensis herb | C | 1 | — | — | — | — | — |
| crocin compound | C | 1 | Mapped | — | — | Mapped | — |
| forskolin compound | C | 1 | — | — | — | — | — |
| Fucoxanthin compound | C | 1 | — | — | — | — | — |
| GABA (Oral) compound | C | 1 | — | — | — | — | — |
| Garcinia Cambogia Extract compound | C | 1 | — | — | — | — | — |
| Guayusa herb | C | 1 | — | — | — | — | — |
| Hawthorn Extract compound | C | 1 | — | — | — | — | — |
| Maitake D-fraction herb | C | 1 | — | — | — | — | — |
| MCT Oil compound | C | 1 | Mapped | — | — | — | Mapped |
| Mulberry Leaf herb | C | 1 | — | — | — | — | Mapped |
| Psyllium herb | C | 1 | — | — | — | — | — |
| Raspberry Leaf herb | C | 1 | — | — | — | — | — |
A blank outcome cell means that outcome is not mapped in this dataset—not that the ingredient has been proven ineffective. Human-study counts use canonical primary-human studies when available; publications explicitly proven to come from the same underlying trial or cohort are counted once. Missing lineage is never assumed to mean duplicate evidence.
Educational research tool
These matrices summarize structured reference data. They do not diagnose conditions, choose treatment, establish pregnancy safety, or determine whether a medication-supplement combination is appropriate for an individual.